Total cholesterol Every kind of cholesterol, added up

Also called TC and Serum cholesterol Often on a standard checkup No fasting needed

The short answer

Total cholesterol adds up all the cholesterol in your blood, including HDL, which isn’t one of the plaque-building kinds. Under 200 mg/dL is called desirable. But because it mixes the two, the same total can mean very different things for your heart.1,2

A good result
Under 200 mg/dL is called desirable.2 What counts more is how much of it is the plaque-building kind: subtract your HDL to get your non-HDL cholesterol.1
If yours is high
Check what’s driving it. A high HDL can push the total up while the plaque-building part stays normal; a high LDL or non-HDL is what to act on.1
Should you test?
Yes. It comes with every standard cholesterol test, which US guidelines recommend for all adults at least every 5 years from age 19, and more often if you have risk factors.1

Check your result

Type the number from your report. It stays on this page.

200 240
  • Desirable Under 200
  • Borderline high 200 to 239
  • High 240 or more

Enter your result to see what it means and what to do next.

Got a result from another lab? Ask Picardo about it. The app explains your results, and a physician can follow up.

Categories from the National Cholesterol Education Program.2 Today’s US guidelines set goals for LDL and non-HDL cholesterol instead, and use your total to estimate your risk.1 The bar isn’t to scale.

What is a normal total cholesterol level?

Labs still report total cholesterol against these long-standing categories.2 Each is a starting point, not a verdict: what to do depends on how much of your total is HDL.

Desirable Under 200 mg/dL

In the desirable range

Your total is under the 200 cutoff.2 That’s usually reassuring, but a low HDL can keep a total under 200 while the plaque-building part is high, so check the breakdown.1

How worried to be

Nothing to worry about on its own.

What to do next
  1. 1 Subtract your HDL to get your non-HDL. Along with LDL, it’s the number US guidelines set goals for.1
  2. 2 If you have high triglycerides, diabetes or extra weight, ask about ApoB. It can be high even when your cholesterol looks normal.1
Borderline high 200 to 239 mg/dL

Borderline high

Your total is a little above the desirable range.2 On its own, that doesn’t say much: if a high HDL makes up the difference, your plaque-building cholesterol may be normal. If not, your LDL and non-HDL will be up too.1

How worried to be

Not urgent. Look at the breakdown before deciding anything.

What to do next
  1. 1 Work out your non-HDL: your total minus your HDL.1
  2. 2 Ask a clinician to estimate your 10-year heart risk. The PREVENT calculator that US guidelines use takes your total cholesterol and HDL, along with your age, blood pressure and other factors.1
  3. 3 If your LDL or non-HDL is high, start with food: swap saturated fat for unsaturated fat.1
  4. 4 Add Lp(a) if you’ve never had it measured. It’s mostly inherited, and US guidelines recommend checking it at least once.1
High 240 mg/dL or higher

High, and worth a clinician visit

Unless your HDL is very high, a total this high means your non-HDL is high too. A non-HDL that stays at 190 to 219 counts as a risk-enhancing factor in US guidelines, and an LDL of 190 or more makes you a candidate for a statin whatever your calculated risk.1

How worried to be

Book an appointment in the next few weeks. It isn’t an emergency.

What to do next
  1. 1 See a clinician to go over your LDL and non-HDL and estimate your overall risk.1
  2. 2 With an LDL of 190 or more, ask about familial hypercholesterolemia, an inherited form. Close relatives would need checking too.1
  3. 3 Check your thyroid: an underactive thyroid raises cholesterol.1
Heart Health panel
$150.90 · Total cholesterol plus 16 more tests, one visit
Order

What is total cholesterol?

Think of total cholesterol as the total on a shopping receipt. It tells you how much you spent, but not on what. Two receipts with the same total can hold very different shopping, and your HDL and non-HDL are the itemized list.

A standard cholesterol test measures three things directly: total cholesterol, HDL cholesterol and triglycerides. LDL and non-HDL are calculated from them.1

Non-HDL is your total minus your HDL. It’s the cholesterol inside every particle that can build plaque, LDL included. HDL particles aren’t among them, which is why counting HDL in the total blurs the picture.1

Is total cholesterol a good measure of heart risk?

Not on its own. In a pooled analysis of 61 studies, total cholesterol divided by HDL predicted death from heart disease more than twice as well as total cholesterol alone.3

Two people with the same total show why:

Person A Person B
Total cholesterol210210
HDL7535
Non-HDL (total minus HDL)135175
LDL122139
Triglycerides75200

Made-up numbers to show the idea, all in mg/dL.

Person B has 40 mg/dL more of the plaque-building kind, along with the low HDL and high triglycerides that often go with insulin resistance.1 Their LDL is only a little higher, so LDL alone would understate the gap. With triglycerides of 150 or more, US guidelines prefer non-HDL or ApoB to LDL for this reason.1

What should you look at instead of total cholesterol?

The numbers that split it up:

  • LDL cholesterol: the main target of treatment. US guidelines set LDL goals by your level of risk.1
  • Non-HDL cholesterol: total minus HDL, so it costs nothing extra. It predicts risk better than LDL, especially when triglycerides are 150 or more.1
  • ApoB: a direct count of the plaque-building particles. Guidelines use it to look for leftover risk once LDL and non-HDL are at goal, especially with high triglycerides or diabetes.1

Read the ApoB guide

Why is total cholesterol still measured?

The other numbers come from it. Subtracting HDL gives your non-HDL, and labs use the total to estimate LDL.1

It also feeds the PREVENT calculator, which US guidelines use to estimate your chance of a heart attack or stroke over the next 10 years. The calculator asks for your total cholesterol and HDL, along with your age, sex, blood pressure, diabetes, smoking and kidney function.1 Behind the scenes, it turns your total and HDL into non-HDL.4

What raises total cholesterol?

Mostly the things that raise LDL:1

  • Your genes, including familial hypercholesterolemia
  • Food high in saturated or trans fat
  • Weight gain
  • An underactive thyroid, kidney disease and some liver diseases
  • Some medicines, including steroids, estrogens and some antipsychotics
  • Menopause and pregnancy

A high HDL raises your total too, though HDL isn’t plaque-building cholesterol.1

How to lower total cholesterol

Aim at LDL and non-HDL, the parts guidelines set goals for, rather than at the total.1

  • Statins

    Lower LDL cholesterol by 30% to 49% at moderate doses and by 50% or more at high doses, and your total falls with it.1

    How much it helps
    A lot
    How sure we are
    Very sure
  • Swapping saturated fat for unsaturated fat

    Butter, fatty meat, full-fat dairy and coconut or palm oil for olive oil, nuts, seeds and fish. It lowers LDL more reliably than cutting cholesterol from your diet.1

    How much it helps
    Some
    How sure we are
    Fairly sure
  • Nuts, soy, fiber and plant sterols

    Eaten together, as in the Portfolio diet, they lowered LDL by 26 mg/dL on average in a trial.1

    How much it helps
    Some
    How sure we are
    Fairly sure

How to get a total cholesterol test, and what it costs

It comes from the lipid panel, which costs $4.50 through Picardo. The Heart Health panel adds 16 more tests from the same visit for $150.90.

Recommended

Heart Health panel

$150.90
17 tests · fast for 12 hours first

Total cholesterol can’t say which kind you have. The panel splits it up, with ApoB and LDL particle number for the plaque-building particles, and adds Lp(a), hs-CRP, blood sugar and thyroid tests. See what’s in it

Just this test

Lipid panel

$4.50
Labcorp 303756 · no fasting needed

The test this number comes from.

  • Results in 2 to 3 days, in the app
  • Physician follow-up if you want one
  • Free Labcorp draw, or $75 at home
  • No other fees. HSA and FSA eligible.

Questions people ask

Do I need to fast for a cholesterol test?

No. After a typical meal, total cholesterol is at most about 8 mg/dL lower on average, too little to matter.5 US guidelines say a non-fasting test is fine for most people; fasting matters mainly if your triglycerides are high.1

What is a normal total cholesterol for my age?

For adults, the same categories apply at every age, with under 200 mg/dL desirable.2 For children and teens, under 170 is acceptable. Cholesterol dips by 10% to 20% during puberty, then rises to adult levels.1

Is the cholesterol ratio useful?

Total cholesterol divided by HDL predicts death from heart disease better than total cholesterol alone.3 But US guidelines set goals for LDL and non-HDL cholesterol, so those are the numbers to track.1

Should I take a statin if my total cholesterol is high?

Not because of total cholesterol alone. US guidelines base the decision on your LDL and your 10-year risk, along with things the calculator leaves out, such as family history and Lp(a).1

How fast can total cholesterol come down?

Within weeks. Clinicians recheck 4 to 12 weeks after starting or changing treatment, then every 6 to 12 months.1 Statins lower it the most; food changes lower it more modestly.1

Test details

Labcorp test
Lipid Panel, 303756
LOINC
2093-3
Sample
Blood
Fasting
Not needed5
Typical lab range
100 to 199 mg/dL
Units
mg/dL in the US. For mmol/L, divide by 38.6.1

Sources

  1. 1 Blumenthal RS, Morris PB, Gaudino M, et al. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of dyslipidemia. Circulation. 2026;153(17):e1154–e1276. doi.org/10.1161/CIR.0000000000001423
  2. 2 National Cholesterol Education Program. ATP III guidelines at-a-glance: quick desk reference. NIH publication no. 01-3305. Bethesda, MD: National Heart, Lung, and Blood Institute; 2001. www.nhlbi.nih.gov/files/docs/guidelines/atglance.pdf
  3. 3 Prospective Studies Collaboration; Lewington S, Whitlock G, Clarke R, et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet. 2007;370(9602):1829–1839. doi.org/10.1016/S0140-6736(07)61778-4
  4. 4 Khan SS, Matsushita K, Sang Y, et al. Development and validation of the American Heart Association’s PREVENT equations. Circulation. 2024;149(6):430–449. doi.org/10.1161/CIRCULATIONAHA.123.067626
  5. 5 Nordestgaard BG, Langsted A, Mora S, et al. Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine. Eur Heart J. 2016;37(25):1944–1958. doi.org/10.1093/eurheartj/ehw152

Updated 28 Oct 2026.

This is general health information, not medical advice: talk to your clinician about your results and before changing any treatment.